Botox rejuvenation is the most popular aesthetic treatment in the world. Botox effectively removes wrinkles from the forehead, those caused by frowning or squinting and wrinkles around the eyes. It can additionally remove wrinkles around the nose and raises the eyebrows, lip angles, and can tighten and smooth the neck region. Botox treatment usually lasts for 3 to 4 months and sometimes up to 6 months. Botox is in the purified protein obtained from the Clostidium botulinum bacteria. Recently, a popular treatment called ‘baby botox’ which removes a large majority of unwanted wrinkle lines with the retention of facial mimicry is performed with a smaller number of units. It is possible that the effect lasts somewhat shorter than standard botox. In Croatia, Allergan botulinum toxin is available in a 50-unit Vistabel® packaging and is fully registered for aesthetic application.